Recommendations From the Advisory Committee on Immunization Practices for COVID-19 Vaccination Implementation

WHO Coronavirus Disease (COVID-19) Dashboard

COVID 19 When will it be Ready?

The topic of a COVID 19 is on everyone's mind as well as when and if a vaccine will become available. We hear different stories from President Trump, Anthony Fauci, M.D., and other sources.  It has been reported China, Russia, and other countries already have the vaccine and are beginning the immunization process.

Historically the United States is often one of the last countries to approve drugs and devices for marketing. This has always been the process.  All new drugs, vaccines, and medical devices must pass three clinical trials.  This can take several years or more.  Scientific advances in viral science such as CRISPR, gene splicing, and vaccine manufacturing have reduced the time to market and reduced the risk of serious complications.  Previously viral particles were developed in chicken eggs, denatured (killed) and the resulting antigen injected into humans after trials in animals such as pigs.  Primate testing was eliminated due to ethical concerns years ago.  Today a COVID 19 particle can be reverse-engineered so that it is not necessary to use an entire viral particle.  Only the protein of the viral wall (the spike on the COVID 19 particle needs to be used to produce a vaccine. 

This much has already been accomplished by multiple manufacturers and several vaccines are in clinical trials.  During the earlier phases of clinical testing, several early vaccines were disqualified due to serious side effects. 

Numerous estimates for completion and release of a vaccine range from two months to mid-2021. The approval process has been truncated considerably.

There will be significant time needed for distribution and supply chain logistics will be significant.

Not everyone will want to be inoculated.  Even today there are many skeptics about the worth of vaccination.  Different vaccines yield different efficacy.

The length of a clinical trial III can determine if side effects will be recognized prio to release. Time will tell after at least six to 12 months elapse.   The number of trial patients is relatively limited in this study.

Health Train Express makes no recomendation as to the efficacy, safety or use of any pharmaceutical products discussed in this letter.  This is a fluid and dynamic situation for the forseeable future.

Credit and attribution is given to the authors noted in this article.  Continue to distance, wear masking and sanitization .

Scientific and Ethical Principles Underlying Recommendations From the Advisory Committee on Immunization Practices for COVID-19 Vaccination Implementation | Infectious Diseases | JAMA | JAMA Network